Urban areas, already home to the majority of the world's population, are expanding and causing global ecological changes. The authors aim to educate students across various disciplines about caring for urban environments and their inhabitants—humans, animals, and plants. They cover environmental and ecological sciences relevant to cities, the connections between urban nature and human health, urban food production, and strategies for valuing urban ecosystems. The authors also discuss responsibilities for urban green spaces, ecological management practices, and the adoption of nature-based solutions to foster a more sustainable urban future. Their goal is to ensure cities can mitigate climate change impacts and enhance their livability and sustainability.